valium half life elderly

Furthermore alterations in phar. Oxazepam and diazepam were compared in healthy elderly volunteers.


How Long Valium Stays In Your System How Long It Lasts

Longer half-lives such as chlor-diazepoxide diazepam and flu-razepam are more likely to accumu-late in the body and cause prolonged sedation 10.

. In full term infants elimination half-lives around 30 hours have been reported with. Valium is a long-acting benzodiazepine with a half-life of up to 48 hours which means it can be active in the body for a few days. The elderly especially if the dose.

Valium is generally prescribed to be taken in doses between. There is a high prevalence of long-term benzodiazepine use among elderly persons persons aged 65 years or older who account for 125 percent of the general. In children 3 - 8 years old the mean half-life of diazepam has been reported to be 18 hours.

In children 3 - 8 years old the mean half-life of diazepam has been reported to be 18 hours. In full term infants elimination half-lives around 30 hours have been reported with. Diazepam accumulates upon multiple dosing and the terminal elimination half-life is slightly prolonged.

9Volume of distribution of diazepam is increased almost twofold in older patients 9the elimination half-life is prolonged from 24 hours. Once diazepam breaks down into these substances they can be eliminated from the. Absorption of diazepam was faster than oxazepam and onset of clinical effects were more pro.

Oxazepam has a half-life of 4-15 hours while temazepam has a half-life of 8-22 hours.


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